Happy New Year

The first day of 2009 is a raining and freezing cold day, but wish the year will be full of sunshine, happiness, and productive for myself and for you, the reader of this blog if there is any.
Twenty years ago (I cannot believe this long!!), I wrote my wishes for the new year at the end of a notebook and sealed the pages for years. Well, I have all the wishes fulfilled. For the past two years, I really made no much progress in my career. I guess I have not worked hard enough. Nevertheless, I have not lost faith in myself and my future and I believe I reach the dream I kept and the life ahead is going to be meaningful, colorful and worthy to pursue.
Here is a short list for my wishes in 2009.
1) Next stop, Paris, Berlin, London or Iceland.
2) Able to explore chemical space and get in touch with the first livable planet in it.
3) The first fund from CNSF.
4) Some meaningful advancement in understanding nano-device.
5) Well, I have more wishes but should not be too greedy. So leave them to the future.

Merry Christmas

Wish everyone a merry Christmas and a happy new year. No matter how hard has 2008 meant to you,the new year is full of wonders and waiting to be picked.

Background image, Scanning tunneling microscope (STM) image of the complex of hexa-para-tert-butylphenylbenzene-Cu2 on Cu(111) surface due to Dr. Leo Gross, IBM Research, Switzerland.

"Marriage Theorem" Revisted

The marriage theorem discussed in a preivous post has been established in Graph Theory. The following theorem appeared in the book titled Introduction to Graph Theroem by Gary Chartrand and Ping Zhang.

In a collection of r women and s men, where 1<=r<=s, a total of r marriages between acquainted couples is possible if and only if for each integer k with 1<=k<=r, every subset of k women is collectively acquainted with at least k men.

The theorem deals with the matching problem between two sets in Graph Theory. Anoother form of the theorem is as following,

Let G be a bipartite graph with partite sets U and W such that r=|U|<=
|W|. Then G contains a matching of cardinality r if and only if U is neighborly.

Neighborly is defined as following,

Let G be a bipartite graph with partite sets U and W such that |U|<=|W|. For a nonempty set X of U, the neighborhood N(x) of X is the union of the neighborhoods N(x), where x blelongs to X. Equivalently, N(x) consists of all those vertices of W that are neighbors of one or more vertices in X. The partite set U is said to be neighborly if |N(x)|>=|X| for every nonempty subset X of U.

In plain words, if there is a subset of U which colletively know fewer members of W than the number of themselves, it will be impossible to find a 1-to-1 match for U from W.

"Spotless" Sun Causes Worries

The Sun has been "spotless" for more than 200 days this year and the longest period since 1954. Scientists are not sure what it does mean, whether the unusual quietness of the Sun is beneficial to the human-warmed-up climate of our earth or bringing serious damage to the earth livings.

Exploring Chemical Space

Chemical space is definitely vast and sparse. There are many problems to be answered.
What is size of the space?
How to chart the space? Using shape descriptors, topology descriptors, property descriptors, similarity to representative molecules, or other measures? Is there something as pure and pretty as primes for the numbers? Is the PCA (principal component analysis) method the only tool to establish the coordinates the axes of the space? Are there fundamental theories from mathematics that can be applied into this area?
Can we learn the structure and the pattern of the chemical space, as clearly as we know about the space universe? What are the driving forces that lie beneath the distribution of the molecules (all available compounds, natural products molecules, drug molecules) in the chemical space?
Is indeed it that there are some collective differences that distinguish the drugs out the rest of the chemical space? If so, what are they? Can we use such knowledge to build the drug-molecules library? If not, what are the effective routes to explore each drug molecule in the chemical space?
It all seemed that we are still very limited to the knowledge of the chemical space, compared with our marvelous understanding about the galaxy and the rest of the space universe.

Diseasome

Diseasome is in fashion. Such a networked map of diseasome appears on the New York Times. Once again, it is proved that a picture is worth a thousand words.
The news article is by ANDREW POLLACK and published on May 6, 2008.
http://www.nytimes.com/2008/05/06/health/research/06dise.html?_r=1&ref=health&oref=slogin

Spectacular Firework from Bird's Nest

Image source: The New York Times, Aug. 24, 2008.
China won the applause of the world with an impossible Olympics show in anywhere but Beijing.

Beijing had staked everything on the Games, galvanizing the nation, spending billions to rebuild the ancient capital, erecting fantastic stadiums and producing the kind of opening and closing ceremonies that can only be created in China, with tens of thousands of performers dazzling a global television audience the vibrant displays of color and mass synchronization.

心经

吾用心追求爱，小心呵护，却未见希望之成长，而跌至深渊。九九八十一难，终要历炼。

玄奘西行取经，历经千辛万苦，终成高僧，译众多佛家典籍，而以精炼的《心经》最为世人所知。

观自在菩萨，行深般若波罗蜜多时，照见五蕴皆空，度一切苦厄。舍利子，色不异空，空不异色，色即是空，空即是色，受想行识， 亦复如是。舍利子，是诸法空相，不生不灭， 不垢不净，不增不减。是故空中无色，无受想行识，无眼耳鼻舌身意，无色声香味触法， 无眼界，乃至无意识界，无无明，亦无无明尽，乃至无老死，亦无老死尽。无苦集灭道， 无智亦无得，以无所得故。菩提萨埵，依般若波罗蜜多故，心无挂碍，无挂碍故，无有恐怖，远离颠倒梦想，究竟涅槃。三世诸佛， 依般若波罗蜜多故，得阿耨多罗三藐三菩提。故知般若波罗蜜多是大神咒，是大明咒， 是无上咒，是无等等咒，能除一切苦，真实不虚。故说般若波罗蜜多咒，即说咒曰：揭谛揭谛，波罗揭谛，波罗僧揭谛，菩提娑婆诃。

最近读王守仁。其少时追求人生之终极意义，参悟“理”与“心”。经“格竹”等磨难，终顿悟心乃理之所以，理乃心之所存，实践知行合一，成就哲学圣人。 吾未曾用心，何来顿悟？ 烦恼终将过去，明日太阳会灿烂.

A Different Kind Of Nothingness

Photo Source: Evelyn Hockstein for The New York Times, Aug 24, 2008.

The sand of Namibia deserts shine in the sun light. The simple and pure colour, the strong contrast between bright and dark make the desert dazzlingly beautiful and attract many tourists to climb the dunes where the roads exist only temporarily. Well, it is certainly not a pleasant living place for many organisms which prefer chaos, organically-disordered chaos. Yes, pureness and simpleness is too good to be healthy to lives.

Love hurts...

It hurts so much.. esp when you thought you have touched the happiness of love and it is blown away.
Pressure amounts. How longer can I endure? Does true love exists?

山城重庆

八月湿热的夏天，3日到重庆逛逛。体会了古镇磁器口，逛了商业繁华之地观音桥、解放碑、三角碑，夜在朝天门看夜景。
垂直的高楼，上上下下的立体路面，浑浊的江水，雾蒙蒙的天气，繁华的街市是我对这一西部发展重镇的第一印象。
次日，雨。在重庆大学信步仙游，遭雨，在民主湖前避雨。湖中荷花虽已过旺季，依旧有娇艳的荷花伴同着即将成熟的饱满莲蓬。正面的湖中有紫色的莲花，我想是小时采过的“鸡头”吧。

两日来，山城之行未从给我带来喜悦开心之情。
夜行归，又想起Akon的Lonely很是贴切自己的心情。

Lonely by Akon

Lonely im so lonely,
I have nobody,
To call my owwnnn
Im so lonely, im mr. Lonely
I have nobody,
To call my owwnnn
Im so lonely,

Yo this one here goes out to all my playas out there ya kno got to have one good girl whose always been there like ya
Kno took all the bullshit then one day she cant take it no more and decides to leave

I wont up in the middle of the night and I noticed my girl wasn't by my side, coulda sworn I was dreamin, for her I was
Feenin, so I hadda take a little ride, back tracking ova these few years, tryna figure out wat I do to make it go bad, cuz
Ever since my girl left me, my whole left life came crashin

Im so lonely (so lonely),
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own) girl

Im so lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own) girl

Cant belive I hadda girl like you and I just let you walk right outta my life, after all I put u thru u still stuck
Around and stayed by my side, what really hurt me is I broke ur heart, baby you were a good girl and I had no right, I
Really wanna make things right, cuz without u in my life girl

Im so lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody to call my own)
To call my own (to call my own) girl

Im so lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own) girl

Been all about the world ain't neva met a girl that can take the things that you been through
Never thought the day would come where you would get up and run and I would be out chasing u
Cuz aint nowhere in the globe id rather be, aint noone in the globe id rather see then the girl of my dreams that made me
Be so happy but now so lonely

So lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own)

Im so lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own) girrll

Never thought that id be alone, I didnt hope you'd be gone this long, I jus want u to come home, so stop playing girl and
Come on home (come on home), baby girl I didn't mean to shout, I want me and you to work it out, I never wished Id ever
Hurt my baby, and its drivin me crazy cuz...

Im so lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own)

Im so lonely (so lonely)
Im mr. Lonely (mr. Lonely)
I have nobody (I have nobody)
To call my own (to call my own) girll

Lonely, so lonely
So lonely, (so lonely),
Mr. Lonely, so lonely
So lonely, so lonely, (so lonely), Mr. Lonely